Disease Management ABOUT OUR FORMULARY FORMULARIES What is a formulary? “Open” Formulary
A formulary is a listing of prescription medications that are preferred for use
A plan that has adopted an “Open” formulary allows coverage for both
by a plan and are dispensed through participating pharmacies to covered
formulary and non-formulary drugs. Drug coverage is not dependent upon
persons. This list is subject to periodic review and modification by the plan.
the formulary list. By adhering to the formulary, the patient will be aiding
their plan in cost-effective pharmacy management.
Our formulary is based on the following criteria: effectiveness, safety (both
of which are established by the FDA), therapeutic role in treatment and
“Closed” Formulary
overall cost effectiveness. All medications on our formulary are FDA
A plan that has adopted a “Closed” formulary ONLY allows coverage of
approved to be safe and effective for their therapeutic indications. This is our
primary consideration when evaluating any medication. Any rebate or
discount that is negotiated with the manufacturing pharmaceutical company
A “closed” formulary affects the coverage of drugs in the following ways:
takes place only after a medication has been recognized as therapeutically
effective. And it is entirely up to a patient’s physician as to whether a certain
Generic drugs are covered at the lowest copayment level. **
medication should be prescribed for said patient. Should a prescription be
written for a non-preferred medication, the patient’s pharmacist may contact
Brand name drugs on the formulary are covered at the lowest
the physician and request substitution with a preferred medication.
copayment level or the middle copayment level, depending on plan
It is best that a patient show this formulary to his/her physician before a
medication is prescribed. This will help to avoid any delay in filling the
Brand name drugs that do not appear on the formulary will not be
prescription should the patient later wish to have a preferred medication as
opposed to a non-preferred medication. All generic medications are included
on the formulary, however, only some are listed due to limited space. Any “Multi-Tier” Formulary new generic medications that are approved by the FDA as
A plan that has adopted a “Multi-Tier” formulary allows coverage for all
therapeutically equivalent and bioequivalent are automatically covered
drugs, however a patient will pay higher copay for brand name drugs that do
under this formulary in accordance with plan policy. We believe, in general, that generic drugs are the most cost effective medications in many cases since they are far lower in price than brand name drugs and
Generic drugs are covered at the lowest copayment level.
since they are older drugs, physicians are more familiar with them in regard to their side effects.
Brand name drugs on the formulary are covered at the lowest
copayment level or the middle copayment level, depending on plan
Note that generic medications are listed on the formulary in lower case letters and brand name medications are listed on the formulary in upper case letters.
Under a “multi-tier” formulary, the patient will be responsible for
BRAND NAME DRUGS: Name identifying a drug as the product of a
specific pharmaceutical company. Also known as proprietary trademark
name. Brand name drugs under patent protection are drugs protected by a patent issued to the original innovator or marketer. The patent prohibits the
manufacture of the drug by other companies without consent of the
innovator, as long as the patent remains in effect. *
PREFERRED BRAND NAME DRUGS: Brand name drugs chosen by our
P. & T. Committee as preferred over other brand name drugs within the same therapeutic class. *
GENERIC DRUGS : Drugs that are approved by the FDA, which have been
shown to be safe and effective, and are therapeutically equivalent and bio-
equivalent to brand name drugs. These drugs contain the identical active
ingredients and amounts as the brand name drugs. However, the generic drugs may be different in appearance in manners such as shape, size or color.
The substitution of brand name drugs with generics will, in virtually all cases,
Therapeutic class and drug form are plan specific and may or may not be covered.
** Not all generic drugs appear on the formulary due to space limitation.
produce the greatest savings for the client.
ANALGESICS HIV Agents
All oral medications used for the treatment of
ANTI-INFECTIVES Influenza Agents Cephalosporins Lincosamides Macrolides Non-steroidal anti-inflammatory agents ANTINEOPLASTIC Nitrofurantoin Penicillins Quinolones Sulfonamides Tetracycline
All oral antineoplastic agents under this class
CARDIOVASCULAR Ace Inhibitors & Combinations: Miscellaneous Hepatitis Agents
* Therapeutic class and drug form are plan specific and may or may not be covered. ** Not all generic drugs appear on the formulary due to space limitation.
Angiotensin Receptor Blockers & Combinations: Bile Acid Sequestrants Miscellaneous Anti-hypertensives: Fibric Acid Derivatives CNS AGENTS HMG-CoA Reductase Inhibitors/Combo Miscellaneous Nicotinic Acids Beta Blockers & Combinations: Calcium Antagonists & Combos:
* Therapeutic class and drug form are plan specific and may or may not be covered. ** Not all generic drugs appear on the formulary due to space limitation.
Biguanides DERMATOLOGICALS EARS, NOSE, & THROAT Combination Products Insulins Meglitinides Miscellaneous Decongestants & Combinations: Sulfonylureas GASTROINTESTINAL AGENTS ENDOCRINE
* Therapeutic class and drug form are plan specific and may or may not be covered. ** Not all generic drugs appear on the formulary due to space limitation.
OPHTHALMIC AGENTS HEMATOLOGY IMMUNOLOGICALS & VACCINES RESPIRATORY AGENTS IMMUNOSUPPRESSANTS NUTRITION Vitamins/Minerals/Electrolyte Modifiers:
* Therapeutic class and drug form are plan specific and may or may not be covered. ** Not all generic drugs appear on the formulary due to space limitation.
SMOKING CESSATION UROLOGICAL AGENTS
DETROL LA oxybutynin oxybutynin ER flavoxate hcl tolterodine TOVIAZ
Benign Prostatic Hypertrophy Agents
doxazosin finasteride tamsulosin caps terazosin
WEIGHT MANAGEMENT
* Therapeutic class and drug form are plan specific and may or may not be covered. ** Not all generic drugs appear on the formulary due to space limitation.
AIFA - Micofenolato Mofetile 20/06/2008 (Livello 2) AIFA - Agenzia Italiana del Farmaco Uso off-label del Micofenolato Mofetile ai Sensi della Legge 648/96 Preso atto che vi possono essere delle sovrapposizioni piu' omeno palesi tra i farmaci inclusi nell'elenco "classico ostorico" della L. 648/96 e quelli contenuti nei cinque elenchi"speciali" di cui alla Determinazione AI
The hSK4 (KCNN4) isoform is the Ca2 ؉ -activated K ؉ channel (Gardos channel) in human red blood cells Joseph F. Hoffman*†, William Joiner*‡, Keith Nehrke§, Olga Potapova*¶, Kristen Foye* ʈ , and Amittha Wickrema** *Departments of Cellular and Molecular Physiology and Pharmacology, Yale University, New Haven, CT 06520; §Department of Medicine, University ofRochester Medical Center, R