Kutirpgcollege.ac.in

Subject: Industrial Chemistry
B.Sc. Third Year Industrial Chemistry
COMPULSORY PAPERS
Paper I – Industrial Chemical Analysis. Paper IV – Chemical Process Economics and Entrepreneurship. SELECTIVE/OPTIONAL PAPERS*
NOTES: -
(i)
*Select any TWO papers out of three. These two papers will be IInd and IIIrd paper
respectively.
(ii)
** The Factory visit of students of B.Sc. IIIrd Year is not compulsory for practical
B.Sc. Third Year Industrial Chemistry
COMPULSORY PAPERS
Paper I – Industrial Chemical Analysis.
1. Sampling procedures, sampling of bulk materials, techniques of sampling – solids, liquids
and gases. Collection and processing of data. 2. Chromatography: Principles, working and applications of – paper chromatography, TLC,
3. Particle size determination, rheological properties of liquids, plastics and their analysis.
4. Modern Instrumental Methods of analysis –
UV-visible spectroscopy
IR spectroscopy and non-dispersive IR
Raman spectroscopy,
NMR Spectroscopy,
Electron spin resonance spectroscopy
Atomic absorption spectroscopy
Flame photometry
Neutron diffraction
X-ray fluorescence
Ion chromatography
Paper IV – Chemical Process Economics and Entrepreneurship.
1. Factors involved in project cost estimation, methods employed for the estimation of
capital investment. Capital formation, elements of cost accounting. Interest and investment costs, time value of money equivalence. 2. Depreciation, methods of determining depreciation. Some aspects of marketing, pricing
policy, profitability criteria, economics of selecting alternatives, variation of cost with capacity, break-even point, optimum batch sizes, production scheduling etc. 3. Need, scope and characteristics of entrepreneurship, special schemes for technical
entrepreneurs development (STED), exposure to demand based, resource based, service based. Import substitute and export promotion industries, criteria for principles of products selection and developments. 4. Choice of technology: plant and equipments. Techno-economic feasibility of the
projects. Plant layout and process planning for the project. 5. Financial Institutions, their procedure and incentives, financial ratio and their
significance. Books of accounts, financial statements and Funds flow analysis. Energy requirement and utilization. 6. Resources management: men, machine and materials. Creativity and Innovations.
Problem solving approach. Strength, weakness, opportunity and threat (SWOT) techniques. 7. Quality control, quality assurance and testing of the product. Packaging and advertising.
8. Sickness in small scale Industries and their remedial measures. Licensing and
registration. Important provisions of Factory Act, sales of goods Act, partnership Act. B.Sc. Third Year Industrial Chemistry
OPTIONAL PAPERS*
Paper 1: Polymers.
1. Brief history of macromolecular science, general characteristics of polymers in
comparison with common organic compounds. Types of polymers - functionality concept, necessity of copolymers and copolymerization, block and graft copolymers. Conducting Polymers. Biopolymers. 2. Methods of polymerization – bulk, suspension, emulsion and solution.
3. Types of polymerizations – addition, condensation, mechanism of polymerization –
free radical, ionic (anionic and cationic), co-ordination polymerization, initiators, inhibitors. 4. Synthesis, chemistry, properties and applications of the following Thermosetting
polymers:-
Phenol-formaldehyde, urea-formaldehyde, melamine-formaldehyde, Polyurethanes,
Polycarbonates, Epoxy resins – grades and curing process, Silicones.
Elastomers – polyisoprene, polybutadiene and neoprene.
5. Synthesis, chemistry, properties and applications of the following Thermoplastics
polymers:-
Polyethylene – HDP, LDP, LLDP. Polyvinyl chloride, Teflon.
Polystyrene – SBR, ABS, SAN.
Vinyl polymers – PVA, PVB.
Polyacetals, Polyamides – nylon-6, nylon-66
Polyethers and Polyesters – terephthalates. Cellulosic polymers.
6. Molecular weight distribution – number, weight and viscosity average molecular
weights of polymers, methods of determining molecular weights. 7. Degradation of polymers by thermal, oxidative, mechanical and chemical methods.
8. Polymer processing – compression molding, casting, extrusion, fibre spinning,
injection molding, thermoforming, vulcanization of elastomers, polymer industry in India. Paper 2: Heavy and Fine chemicals.
1. Heavy Inorganic Chemicals –
Manufacture of following with reference to – (i) Ammonium phosphates, super phosphate, triple super phosphate, carbon blacks, manufacture of graphite and carbon, calcium carbide, silicon carbide, sodium thiosulphate, borax and boric acid. Industrial catalysts – raney nickel, other forms of nickel, palladium and supported
palladium, copper chromate, vanadium and platinum based catalyst. Aluminium alkoxides,
titanium tetrachloride and titanium dioxide.
2. Fine Chemicals –
Manufacture of following with reference to – (i) Sodium borohydrate, lithium aluminium hydride, sodium ethoxide, paracetamol, indigo, vat dyes. Essential oils, surfactants and emulsifying agents, coloring agents- manufacture of some natural and synthetic colors. Flavouring agents – fragrance and food additives. Biochemical reagents – ninhydrin, tetrazolium blue, 1,2-naphthaquinone-4-sulphonate. 3. Heavy Organic Chemicals –
Manufacture of following with reference to – (i) Fischer-tropsch synthesis. Applications and uses of zeolites as catalyst. Propargyl alcohol, 1,4-butanediol, vinyl chloride, pyridines, picolines, phthalic anhydrides, glycerol, sorbitol, chloroform, ethanolamine. Industrial solvents – DMF, DMSO, sulpholane, alkyl pyrrolidone, THF, dioxane. Paper 3: Pharmaceuticals.
1. Historical background and development of pharmaceutical industry in India.
Introduction to pharmacopoeias. Types of formulations and roots of administration. Aseptic conditions, need for sterilization, Method of sterilization. 2. Various types of pharmaceutical excipients – their chemistry, process of
manufacture and quality specifications – Glidants, lubricants, diluents, preservatives, antioxidants, emulsifying agents, coating agents, binders, coloring agents, flavouring agents, gelatin and other additives, sorbitol, mannitol, viscosity builders etc. 3. Evaluation of crude drugs – moisture contents, extractive value, volatile oil
content, foreign organic matter. Quantitative microscopic exercises including of starch, crude fiber content. Various isolation procedures for active ingredients. 4. Chemical constitution of plants – including carbohydrates, amino acids, proteins,
fats, waxes, volatile oils, terpenoids, steroids, saponins, flavonoids, tannins, glycosides, alkaloids. 5. Pharmaceutical Quality Control – sterility testing, pyrogenic testing, glass testing,
6. Raw materials, process of manufacture of the following bulk drugs –
Sulpha drugs – sulphaguanidine, sulphamethoxazole Antimicrobial – chlorampinecol, Na-PAS. Analgesic-anti-inflammatory – salicylic acid and its derivatives, ibuprofen, mefenamic acid. Steroidal hormones – Progesterone, Testosterone, Methyl Testosterone. Vitamins – vitamin-A, vitamin-B6, vitamin-C. Antihistamines – chloropheneramine maleate. Antibiotics drugs – penicillin-G, semi synthetic penicillin, rifamycin, tetracycline, and vitamin-B12. Antimalarial drugs. Anticancerous drugs. AntiAIDS vaccines. 7. Brief idea of microorganisms - their structure, growth and usefulness.
Biotransformation processes – for prednisolone, 11-hydroxylation in steroids.
Enzyme systems - useful for transformation, microbial products, enzyme catalyzed
transformation - manufacture of ephedrine.
Practical**:
1. Synthesis of common industrial compounds involving two step reactions, e.g. 4-bromo
aniline, 3-nitroaniline, sulphanilamide, 4-amino benzoic acid, 4-nitro benzoic acid, dihalobenzenes, nitrohalobenzenes, paracetamol, oils of winter green. 2. Determination of acid value, Iodine value and saponification value.
3. Instrumental methods of analysis – colorimeter, flame photometer.
4. Preparation of urea formaldehyde resin.
5. Industrial analysis – analysis of common raw materials as per the industrial
specifications such as phenol, aniline, formaldehyde, hydrogen peroxide, acetone, etc. 6. Limit tests for chlorine, heavy metals, arsenic of drugs.
7. Determination of sulphate ash, loss on drying of drugs.
8. Identification of drugs by TLC.

Source: http://www.kutirpgcollege.ac.in/Syllabus/IndChem3.pdf