Roy M. Poses MD President, the Foundation for Integrity and Responsibility in Medicine (FIRM) http://www.firmfound.org/ Associate Clinical Professor of Medicine Brown University
– Institute of Medicine’s Crossing the Quality Chasm:
“quality problems are everywhere, affecting many patients.”
– Medicare fee cuts leading to physicians dropping
• There are new calls for health care reform
• Supposed “Aura of inevitability” about health care
– Health care professionals are also increasingly unhappy
– Increased sense we are not getting our money’s worth
• Asked physicians open-ended questions about their
concerns about what is going wrong with health care
• Compiled and described their major themes in “A
Cautionary Tale: The Dysfunction of American Health Care”
• Examples sought in health care literature and media
– Tips from physicians, crude search attempts and ongoing
– Little yield from medical and health care literature
• Little systematic research yet reported
Poses RM. Eur J Int Med 2003; 14: 123.
• Physicians felt that their core values are externally threatened
• They cited numerous local examples of
concentration and abuse of power
– Health care is increasingly dominated by large
organizations whose goals may not be aligned with physicians’ professional values
– Such organizations may be led by the ill-
informed, the unethical, or even the criminal
• Most physicians could cite local examples of
• Most thought their examples were unique, and that
they were particularly unfortunate to work in proximity to it
• Most had not heard of examples from outside their
• Most did not recognize concentration and abuse of
The Allegheny Health Education and Research
• From Allegheny General Hospital in Pittsburgh (1968) to largest
health care system in Pennsylvania (1997)
• CEO was Sherif Abdelhak, called a “visionary,” “genius,” gave John
D. Cooper Lecture at AAMC (1996), published in Academic Medicine
• By 1995, Abdelhak earned $1.2 M, 3 times the median for a health
• In 1997, although Abdelhak was still publicly announcing expansion
• In 1998, Abdelhak fired, AHERF declared Chapter 11 bankruptcy,
$1.2 billion in debt, second largest bankruptcy in US at that time
• Allegheny University of Health Sciences downsized, multiple
hospitals closed, multiple lay-offs, multiple lawsuits filed
• After plea bargain, Abdelhak sentenced to 11-23 months for raiding
The Allegheny Health Education and Research
– “colossal disaster that could have been avoided”
– “obscene,” “an atrocity,” “repugnant”
– Abdelhak was “an evil person” who “never took
responsibility for bringing the system down”
The Allegheny Health Education and Research
Foundation (AHERF) Case: National Responses
Tepid responses of national organizations:
– CEO of American Association of Medical Colleges: “unprecedented for a medical school
to be caught up in this type of bankruptcy”
– Liaison Committee for Medical Education: would help place students if AUHS bankrupt– Joint Commission on Accreditation of Healthcare Organizations: Hahnemann Hospital
– Physicians’ organizations, like AMA, ACP, AAFP, etc - ?– Academic boards, like ACGME, ABIM, federal agencies, etc - ?
One article in Health Affairs, covered only through mid-1999, but not outcome of most legal proceedings [1]
Nothing in any large-circulation journal (including news sections)
Nothing in Academic Medicine since Abdelhak’s paper
First article that mentioned Abdelhak’s conviction: Poses in Euro J Int Med in 2003[2]
1. Burns LR. Health Affairs 2000; 19: 7. 2. Poses RM. Eur J Int Med
– Hermann Hospital’s managers convicted of theft– Seven convicted for embezzling >$20 M from Cooper Hospital/UMC – AMA endorsed Sunbeam, AMA endorsed alteplase for cash
– NIH leaders got six-figure consulting fees from pharma– Hospital CEOs fired for ethical lapses: Fletcher Allen (convicted of conspiracy),
Bellevue, Jacobi, Staten Island University (EVP), Roger Williams (convicted of conspiracy and mail fraud) UC- Irvine, Caritas Christi
– UMDNJ President, board members, other leaders resign, now operating under
• Have American physicians (or health care researchers, or health policy makers) ever heard of them?
• The “recent unpleasantness” - most cases have only
been discussed locally, and only in news media
• Academia and medical/ health care/ health policy
literature, medical organizations mostly silent
• Until recently, doctors sometimes complained
• Therefore, no recognition of more wide-spread and
• Those who are ignorant of history are bound to
• Pervasive “conflicts of interest”
• Health care institutions revered since days
when they were small, relatively thread-bare, mission oriented
• The cult of the “imperial CEO” leads to
– The institution and the leaders are one
• In academic medicine, the dogma is that “conflicts
of interest” are inevitable, and should be “disclosed” and “managed,” but not eliminated
• Many such “conflicts of interest” fit Transparency
International’s definition of corruption:
– Abuse of entrusted power for private gain
• Medical academics are entrusted to seek and
• For a medical academic to help promote a
commercial product or service in his or her guise as an academic can be abuse of entrusted power
• For an academic to do so while personally being
paid or otherwise rewarded by the commercial provider of the product or service can be
– Abuse of entrusted power for private gain
– Often speak or write under academic auspices
in ways that promote the companies’ products
– May fail to disclose the nature, size, and
intensity of their relationships to the companies, and only in fine print
physicians as “key opinion leaders” to market product
• Low level, most common – small gifts, meals,
trips to students, house-staff, faculty from industry
• Mid level, common – speaking fees, consulting
fees, etc to faculty “thought-leaders”
• High level, less common – service on for-profit
health care corporations’ boards of directors (plus fees and stock options) for senior faculty, medical school and university leaders
• Almost half of faculty reported conflicts
• More than one-third of academic leaders
• 7/10 members of conflicts of interest
• Gave talks, wrote articles, and lead government research
grant on mifespristone as treatment of depression
• Simultaneously sat on board of directors and scientific
advisory board of, and held 3 million shares of company that sought to get approval to market mifepristone as treatment of depression
• Failed to reveal the nature and intensity of his financial
relationships with the company in published articles that were positive about the drug
– Article only said study was “supported by a grant” from the
company, and that the chair of psychiatry had “a financial interest in” it.
• Parke-Davis’ strategy for marketing gabapentin
– Recruited physicians who could influence colleagues
– Recruited “thought leaders,” “key influencers,” and
“movers and shakers” (department chairs, vice-chairs, directors of academic programs or divisions)
– Speakers bureaus were meant to “identify and train
– Recruited academics as authors of articles to be
Steinman MA et al. Ann Intern Med 2006; 145: 284
– Staff and leaders of health care or medical not-for-
profit organizations and non-governmental organizations (NGOs)
– Staff and leaders of health care or medical government
• People with conflicts of interest “often find giving clear advice (or opinions) particularly difficult.”
– Joe Collier, “The Price of Independence”
• Many in academics, not-for-profits/ NGOs,
government have “conflicts of interest”
• Many more work with or for someone with
• In this context, conflict aversion, political
correctness, and fear of retaliation may produce silence
• Unethical behavior, corruption, criminality may be
common in health care in developed countries
• The issue is largely unstudied; but many practitioners are
• The issue may remain hidden, without echoes, “anechoic”
– Outdated reverence– L’hospital c’est moi– Pervasive “conflicts of interest”– Political correctness and the like
• Until the issue is widely discussed, we are unlikely to
The "Win-Win" initiative: a global, scientifically based approach to resource sparing treatment for systemic breast cancer therapy Ahmed Elzawawy 1,2,3,4,5 1Clinical Oncology Department, Faculty of Medicine, Suez Canal University, Egypt 2Alsoliman Radiation Oncology Unit, Port Said, Egypt 3Early Detection and Cancer Chemotherapy Unit, Port Said General Hospital, Egypt 4ICEDOC: Inte
Code review /ProgramOverModule11Purpose of the module: the module displays statistics about a program. All available programs can be selected. The list of indicators is static. The user can select to display a graph. Maintainability - JUnit AdminListExtensionTest fails, no other test cases implemented - Design: org.openmrs.module.programOver.web.controller.ProgramPatientsController is not a Spr