Dr.V.M.Chandrashekhar Department of Pharmacology Research M.Pharm projects: 15
1. Evaluation of cardiaoprotective activity of Abutilon indicum in albino rats-
2. Hepatoprotective activity of Stereospermum suaveolens on Albino rats- 2007. 3. Antiosteoporotic effect of Berberis aristata on ooveriectomized rats-2007. 4. Neuroprotective activity of Matricaria recutita in oxidative stress induced rat
5. Evaluation of anti-arthritic activity of Indicofera tinctoria in albino rats - 2008. 6. Pharmacodyanamic and Pharmacokinetic
Osemoprazole with anti-diabetic agents-2008.
7. Evaluation of anti cancer activity of Moligno olifera on EAC bearing mice-
8. Pharmacodynamic interaction of xanthine oxidase inhibitors wit h piracetamin
and quercetin in ischemia /reperfusion induced oxidative stress-2008.
9. Evaluation of Quinazolinone derivatives as potential anti- inflammatory and
10. Neuroprotective activity of Sterosperum suvelolens DC. against global
cerebral ischemia and Parkinson’s disease in rat model-2009.
11. Evaluation of anticancer activity of Marine Zoanthus Spp.in EAC bearing
12. Antigenotoxic effects of Chamomile tea and Black tea against
cyclophosphamide inducing genotoxicity in swiss albino mice
13. Pharmacological studies on Matricaria recutita L. in acute and chronic
14. Neuroprotective activity of Berberis aristata DC against Global cerebral
ischemia and Parkinson’s disease in rat model.
15. Evaluation of anti-osteoporosis activity of marine Zoanthus Sp.on SD rats.
Publications: Papers published in International and National scientific Journals: 23
1. Rekha S. Hunoor, Basavaraj R. Patil, Dayananda S. Badiger, Ramesh
V.M. Chandrashekhar and
S.Muchchandi. Synthesis, characterization, anti- inflammatory and analgesic activity
Organometallic Chemistry. 2011, 25, 6, 407-485.
2. Prasahant D.Phadatare, V.M.Chandrashekhar. Influence of esomeprazole on
hypoglycemic activity of oral anti-diabetic agents in rats and rabbits. Molecular and Cellular Biochemistry, Article in Press: DOI: 10.1007/s11010-011-0812-7.
V.M.Chandrashekhar,
Ragavendra, Giresh.K.Gowda, B.Goplakrishna. Anti-osteoporotic activity of
aqueous- methanol extract of Berberis aristata in ovariectomized rats. Journal of Ethnopharmacology, 2011,134, 334-338. .DOI: 10.1016/j.jep 2010.12.013
4. Vishawas L.Ranpariya, S.K.Parmar, N.R.Seth, V.M.Chandras hekhar,
Neuroprotective activity of Matricaria recutita against fluoride induced stress in
5. Rekha Shankar Hinoor, Basavaraj Rudragouda Pate l, Dayananda Shivappa
Badiger, Ramesh Shivananadappa Vadavi, Kalagouda Basappa Gudasi, Chandras hekhar Venkaraddi Magannavar, Irran Sangappa Muchandi. Spectroscopic, magnetic and thermal studies of Co(II), Ni(II),Cu (II) and Zn (II) complexes of 3-acetylcoumarin- isonicotinoylhydrazone and their antimicrobial and anti-tubercular activity evaluation. Spectrochemica Acta Part A, 77, 2010, 838-844.
6. V.M.Chandrashekhar,
A.A.Muchandi. Neuroprotective activity of Matricutita recutita in global ischemia model. Journal of Ethinopharmacology,-65
7. S.Ganapaty, V.M.Chandrashekhar, M.Laxim Narasu Antiallergic activity
of gosspin and suramin in allergic model. Journal of Biochemistry and Biophysics, 2010,47, 90-95
8. Chandras hekhar.V.M, A.Muchandi, Sarasvathi Sodi, Ganapaty, S.
Hepatoprotective activity of Stereospermum suaveolens DC against CCl4–induced hepatotoxicity. Pharmaceutical Biology, 2010, 48 (5), 524-528.
9. H.R.Chitme, Mallikarjun Malipatil, V.M.Chandrashekhar, P.M.Prashant.
Anti-allergic activity of Aristiolochia bracteolate Lank in animal model. Indian Journal of Experimental Biology, 2010, 48, 46-52.
10. S.Ganapaty, V.M.Chandrashekhar, H.R.Chitme, M. Laxmi Narsu, Free
radical scavenging activity of gossypin and nevadensin: An in-vitro evaluation, Indian Journal of Pharmacology, 2007, 39 (6), 281-283.
11. Rekha Shankar Hinoor, Basavaraj Rudragouda Patel, Dayananda Shivappa
Badiger, Ramesh Shivananadappa Vadavi, Kalagouda Basappa Gudasi, Chandras hekhar Venkaraddi Magannavar, Irran Sangappa Muchandi. A study of Ant-inflammatory and analgesic activity of New 2,3-Disubstituted 1,2-Dihydroquinazolin-4(3H)-one Derivative and its Transition Metal Complexes. Chem. Pharm. Bull, 2010, 58 (5), 7122-716. Chandras hekhar.V.M. Anticancer activity of Strychnous potatorum Linn on EAC induced female Balb/C in mice. Indian Journal of Pharmacology, 2009, 42, 1, S26-S27.
14. S.Ganapaty, V.M.Chandrashekhar, M.Laxim Narasu, Antioxidant activity
of gossypin in Aluminium fluoride induced oxidative stress in rats. Communicated for Indian Journal of Pharmacology (In Press)
15. Chandras hekhar.V.M, Muchandi.I.S, Sarasvathi.V.Sodi, Muchandi I.S. Free
radical sacvenging activity of Stereospermum suaveolens DC: An in vitro evaluation. Pharmacologyonline, 2009.1, 50-56.
16. Syed mansoor A, Vrusabendra swamy BM, Gopkumar P, Dhanapal R,
V.M.Chandrashekhar. Anti-diabetic activity of Terminal catappa Linn leaf extract in alloxan induced diabetic rats. Iranian Journal of Pharmacology and Therapeutics, 2005, l4 (1), 33-39. V.M.Chandrashekhar and T.sreenivas Rao. Anti-diarrhoeal activity of Terminal catappa Linn in albino rats. Asian Journal of Chemistry, 2006, 18, 1, 1236-1242.
18. V.M.Chandrashekhar, A.N.Nagappa, T.S.Channesh. Antidiarrhoeal activity
of Abutilon indicum Linn leaf extract, Journal of Natural Remedies, 2004, 41, 12-14.
19. V.M.Chandrashekhar, Abdul Hasseb, A.N.Nagappa. Hepatoprotective
activity of Wrightia tinctoria (roxb) in rats, Indian Drugs, 2004, 41(6), 366-370
20. J.S.Patil, P.V.Habbu, V.M.Chandrashekhar, D.R.kulkarni, R.B.Kotnal,
R.V. Kulkarni, Comparative study of drug utilization pattern between rural and urban setting. The Indian Journal of Hospital Pharmacy, 2004, 188-191.
21. A.N.Nagapa, V.M.Chandrashekhar, K.Giresh. Pharmacovigilance: Need of
the Hour, Parma pulse, 2000, 6, 42.
22. Abstract Published: Masood MK, Sudi SV, Birade Deepa., Patel AK,
Muchandi I.S, Chandrashekhar VM. Anticancer activity of Strychnos potatorum Linn, on EAC induced female Balb/C mice. Indian Journal of Pharmacology, 2009, 41, 1. (Presented at Annual Conference of Indian Pharmacological Society, Dec 10-12, 2009, Kolkata, India.
23. Abstract Published: Patel NM, Prasher A, Ranpariya V, Vadiya JN, Reddy S,
Chandras hekhar.VM. Cardiprotective activity of Abutilon indcum Linn in swimming induced cardiac hypertrophy in albino rats. Indian Journal of Pharmacology, 2009, 41, 1. (Presented at Annual Conference of Indian Pharmacological Society, 2009, 10-12, Kolkata, India Presentations inInte rnational/National Confe rences/Seminars/Symposium: 32 Inte rnational Conferences : 07
1. V.M.Chandrashekhar, Mallappa Shivadi, Deepa.S.Birade, Ramesh. B.
Nidavani. Neuroprotective activity of Stereospermum suaveolens agonist global and 6-OHDA induced Parkinsonism model. Invited speaker, Third International Conference on Natural Products for Health and Beauty Bangkok, Thailand, March 16-18, 2011
2. Raghavendra H.L, Maitree Suttajit, Vidhya Ramaswamy, Chandrashekhar V.M, Vadlapudi Kumar. In vitro antidiabetic, antioxidant and antilipidimic activity of a new phytochemical combination. Third International Conference on Natural Products for Health and Beauty Bangkok, Thailand, March 16-18, 2011-Oral presentation
3. Raghavendra H.L, Maitree Suttaji, Chandras hekhar.V.M, Vadlapudi Kumar.
Phytochemical Combination Regulates Carbohydrate Metabolism and Improves Antioxidant Status in Streptozotocin Induced Diabetes Mellitus. Third International Conference on Natural Products for Health and Beauty Bangkok, Thailand, March 16-18, 2011-Best Poster Awarded (First Prize).
4. Deepa. S. Birade, Chandrashekhar V.M, Raghavendra H.L, Chandraraj. C.
Simpi, Mrutyunjay Bellad, Dipak Biswas1 and B.S. Biradar1 Raju. Anticancer Activity of Marine Zoanthus species on Ehrlich Ascites Carcinoma Bearing Female Balb/c Mice. Third International Conference on Natural Products for Health and Beauty Bangkok, Thailand, March 16-18, 2011-Poster
5. V.M.Chandrashekhar,, S.Ganapaty, Laximi Narsu. Neuroprotective activity
of natural products agonist ischemia/reperfusion induced oxidative stress. Was presented, 27-30th September at Chile, South American, for International conference on Free radical and antioxidant Chile 2009.
6. Vishavas Ranpria,, ////////////////////// Neuroprotective activity of natural
products agonist ischemia/reperfusion induced oxidative stress. Was presented, USA. (Accepted for presentation)
7. V.M. Chandrasekhar, A.N. Nagappa. Antidiarrhoeal activity of Abutilon indicm Linn in Albino rats, Inte rnational conference, FAPA, Sydney (Australia), 27th to 30th October 2000. National Conferences/ Seminars
1. V.M.Chandrashekhar, S.Ganapaty, Laxmi Nasu. Antiallergic activity of
gossypin and suramin , Poster presentation at International Conference on “Advances in Free Radical Research: Natural Products, Antioxidants and Radioprotectors” (AFRR – 2009)8th Annual Meeting of the Society for Free Radical Research – Indiawill be held during March 19-21, at the Scientific Convention Centre, C.S.M. Medical University, Lucknow, India. 2009.
2. Masood MK, Sudi SV, Birade Deepa., Patel AK, Muchandi I.S,
Chandras hekhar VM. Anticancer activity of Strychnos potatorum Linn, on EAC induced female Balb/C mice. Indian Journal of Pharmacology, 2009, 41, 1. (Presented at Annual Conference of Indian Pharmacological Society, Dec 10-12, 2009, Kolkata, India. Chandras hekhar.VM. Cardiprotective activity of Abutilon indcum Linn in swimming induced cardiac hypertrophy in albino rats. Indian Journal of Pharmacology, 2009, 41, 1. (Presented at Annual Conference of Indian Pharmacological Society, 2009, 10-12, Kolkata, India
4. Ashok A. Mucahndi, Ashish Prasher, I.S.Mucahndi, V.M Chandrashekhar.
Anticancer activity of Cynodon dactylon on Swiss mice. Presented at National Level student’s Symposium, Basaveshwar Engineering College, Bagalkot, Karnataka, 21-22 Oct 2008.
5. Yogesh HS, Shombu Kichadi, I.S.Muchndi, V.M Chandrashekhar. Evaluation
of anti-diabetic and nephroprotective activity of Indigofera tinctoria in experimental animals. Presented at National Level student’s Symposium, Basaveshwar Engineering College, Bagalkot, Karnataka, 21-22 Oct 2008.
V.M.Chandras hekhar,
I.S.Muchandi, Antiarthritic potential of Aristolochia bracteata R in albino rats, National Seminar, Current trends in Preclinical and clinical validation of Traditional medicines,18th -19th August Bagalkot, 2007.
7. Shambhu .C. Kichadi, Nitin P.Patil, V.M.Chandrashekhar, H.R.chitme,
I.S.Muchandi, Analgesic and anti- inflammatory activity of Aristolochia bracteata R, National Seminar, Current trends in Preclinical and Clinical validation of Traditional medicines,18th -19th August Bagalkot, 2007.
8. Vishavas L. Ranpariya, V.M.Chandrashekhar, H.R.chitme, I.S.Muchandi,
Transgenic animals and their application in Bio medical research, at National Seminar, Current trends in Preclinical and Clinical validation of Traditional medicines,18th -19th August Bagalkot, 2007.
9. Ashok A.Muchandi, V.M.Chandrashekhar, H.R.Chitme, I.S.Muchandi,
Alternative to laboratory animal Experimentation (In Preclinical Study) , at
National Seminar, Current trends in Preclinical and Clinical validation of Traditional medicines,18th -19th August Bagalkot, 2007.
10. Prashanath P.M, Chandrasekhar. V. M., I.S. Muchandi, H.R.Chitme. In-vivo
and in vitro antiallergic activity of Aristolochia bracteata in compound 48/80 induced mast cell degranulation.at South Indian Pharmacological Society, South regional Conference, 12th -13th July, Pandichery, Andhra Pradesh.2006
11. Azamath.U.M, Chandrasekhar. V. M, Muchandi I.S, H.R.Chitme.
Anticancer activity of Candydon dacitlon EAC induced carcinoma mice. at South Indian Pharmacological Society, South regional Conference, 12th -13th July, Pandichery, Andhra Pradesh.2006
12. V.M.Chandrashekhar,
Pharmacological evaluation of Wrightia tintoria (Roxb) R.Br. In albino rats. National Seminar on Emerging Trends in Ethnopharmacology, Bagalkot, 2005
13. Nanu rathod, M.S.Harish, Shubha hedge, V.M. Chandrasekhar, H.R.Chitme,
I.S.Muchandi, Pharmacogical evaluation of immunostimulant activity of stimune polyhedral formulation, National seminar on Emerging Treads in ethanopharmacology, Bagalkot, 2005.
14. Umesh patil, R.Chanshetty, M.H.Patil, V.M.Chandrashekhar, I.S.Muchandi
Antidiarrhoeal activity of Carrisa carrandas Linn root extract, National Seminar on Emerging Trends in Ethanopharmacology, Bagalkot,2005
.Chandrasekhar,
Antidiarrhoeal activity of Hibiscus esculentus Linn in Albino rats,. In 54th Indian Pharmaceutical Congress, Pune, December 13,14 and 15, 2002
National/International Conferences/Seminars/Symposium Etc., Attended
1. Thailand 2. International conference Free radicals and antioxidant, SFRB South American
3. Advances in Free Radical Research: Natural Products, Antioxidants and
Radioprotectors” (AFRR – 2009)8th Annual Meeting of the Society for Free Radical Research – Indiawillbe held at the Scientific Convention Centre, C.S.M. Medical University, Lucknow, India (2009)
4. South Regional Indian Pharmacological Society, Puduchery ( 2008) 5. 55nd Indian Pharmaceutical Congress, Chennai (2003) 6. 54nd Indian Pharmaceutical Congress, Pune (2002) 7. 53rd Indian Pharmaceutical Congress, New Delhi (2001). 8. International convention of Pharmacy Educators on International Trends in
Pharmaceutical Sciences and Practice, Bangalore (2002).
9. Annual National Convention (7th), APTI, Goa College of Pharmacy, Goa
10. 8th Annual National Convention, APTI, KLE College of Pharmacy, Hubli,