Ananda K Nanjundaswamy 2051 Kerr Dr R-09
Email:[email protected]
Bioprocess development specialist with 8 years of industry experience:
• 5 years experience in development and production of agri-based products like
biopesticides and insect pheromones, production and purification of glycopeptide antibiotics and secondary metabolites from plant tissue culture
• 3 years experience in production and purification of biopharmaceuticals like
QUALIFICATIONS Research coordinator- Managed R&D operations for 4 years, designed and executed research projects, supervised six research associates, set up two operational R&D labs single handedly, coordinated with different state and federal agencies for conducting field trials Team player- Coordinated with R&D team for process optimization and scaling up of statins and mycophenolic acid from pilot scale to production, improved product yields which lead to doubling of the company profits Target achiever-Achieved company targets of timely production of compounds, scaled up product yields and completed projects on time Innovator- Involved in the novel manufacture and purification of compactin and cyclosporin which were patented and also designed a bioreactor CellovenTR for optimizing cell titers in insect cell cultures
INDUSTRY EXPERIENCE Head, R&D A.G. Bio Systems Pvt. Ltd.Single handedly set up two state-of-the art research facilities, one of which was awarded ISO 9001 and supervised six research associates. Designed and managed the following research projects
o Insect pheromones—Identification and commercialization o Bioinsecticides—Production of Bt, Photorhabdus luminescence,
Penicillium oxalicum; Optimized insect cell lines for production of NPV; Designed a bioreactor CellovenTR to enhance the cell titer in insect cell cultures to obtain maximum occlusion bodies of NPV; Optimized an in vitro assay for chitinase
o Biopharmaceuticals—Developed and optimized downstreaming of
glycopeptides like teicoplanin, vancomycin and rifamycin SV
o Bioprospecting—Isolated and screened fungi and actinomycetes for
antibacterials, ovicidals, and insecticidals against Helicoverpa armigera and Spodaptera litura
o Secondary metabolites—Optimized plant cell culture for the production of
vincristine and scopolamine from Catharanthus roseus and Datura stramonium respectively using bioreactors
Consultant Transcorp Technology Ltd. Bangalore, INDIA Conducted field trials of agri-based products and also optimized solid and submerged fermentation of secondary metabolites Scientific Associate, R&D Biocon India Ltd. Bangalore, INDIA Part of the pharma group involved in the optimization, scaling up and purification of compounds like lovastatin, cyclosporine, mycophenolic acid, acarbose and amylase TECHNICAL SKILLS Microbiology—Isolation and preservation of microbial cultures Insect cell lines—Maintenance of Helicoverpa armigera and Spodaptera litura cell lines Insect Pheromones—Identification and commercialization Strain improvement—Random and site-directed mutagenesis Bioprocess development—Solid-sate, submerged; optimization and scale up Protein Science—Purification and identification Compliance activities—GMP, GLC Bioreactors—Operation of different fermenters and SCADA software systems for fermentation control Filtration Chromatography EDUCATION PhDGrain Science (Bioprocessing) MSBiochemistry
University of Agricultural Sciences, Bangalore, INDIA
BS Agriculture
University of Agricultural Sciences, Bangalore, INDIA PATENTS 1. AU 2000255633 (55633/00);WO 01/81611 () Title: A novel process for the manufacture and purification of compactin 2. US7176001; AU 2000235743 (35743/00); WO 01/64935 (
Title: Manufacture and purification of cyclosporine A PUBLICATIONS
Anand KN and Thimmaiah SK (2003). Studies on nitrogen fixation characters in some varieties of cowpea Indian Journal of Plant Physiology 8(4), 354-358
Anand KN, Thimmaiah SK, Mahadevu P (2001). Evaluation of nitrogen fixation and leghemoglobin content in root nodules of cowpea (Vigna unguiculata (L.) Walp.). Indian J Agric Biochem 14 (1 & 2), 69-70
Thimmaiah SK, Anand KN, Mahadevu P (1999). Relationship between ureide content and nitrogen fixation rate in cowpea (Vignaunguiculata (L.) Walp.). Indian J Agric Biochem 12 (1), 27-30
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