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Drug Cl ass: Sulfonylurea
Drug Class: Biguanide
Drug names: Glipizide (Glucotrol®,
Drug names: Metformin (Glucophage®)
Glucotrol® XL), Glyburide (Micronase®,
How does it work?  sugar production from
Glynase®, Diabeta®), Glimepiride (Amaryl®)
How does it work?  insulin secretion from
How is it best taken?
How is it best taken?
What are some possible side effects?
What are some possible side effects?

Drug Class: Thiazolidinedione
Drug Class: Dipeptidyl Peptidase IV
Drug names: Rosiglitazone (Avandia®),
Pioglitazone (Actos®)
Drug name: sitagliptin (Januvia®), saxagliptin
How does it work? This medication works in
(Onglyza®**) lindagliptin (Tradjenta®**) the muscles to help your body use insulin How does it work? Helps increase insulin
How is it best taken?
production; stops the liver from making too  Take at the same time every day - can How is it best taken?
 Take at the same every day – can be What are some possible side effects?
What are some possible side effects?
**Onglyza and Tradjenta not available at FDL pharmacies. Januvia is available with restrictions ** Drug Class: Meglitinide
rug Class: Amylin analog
Drug names: Repaglinide (Prandin®),
Drug name: Pramlintide (Symlin®)
How does it work? Stops the liver from
How does it work?  insulin secretion from
making too much glucose; slows the release How is it best taken?
How is it best taken?
 Inject just before or after mealtime What are some possible side effects?
What are some possible side effects?
**Starlix is not available at FDL pharmacies** Drug Class: -glucosidase inhibitor
Drug Class: Incretin mimetic
Drug names: Exenatide (Byetta®, Bydureon®),
Drug names: Acarbose (Precose®), Miglitol
How does it work? Signals insulin production;
stops the liver from making too much glucose; How does it work? Slows digestion of sugar
How is it best taken?
How is it best taken?
 Byetta®: Inject 1 hour before morning
 Take with the first bite of each meal What are some possible side effects?
 Bydureon®: Injected once weekly  GI upset (diarrhea, gas, belly pain) What are some possible side effects?
**Victoza® and Bydureon® are not available at FDL pharmacies** Drug Class: Insulin
How does it work? Insulin helps cells take in sugar

Rapid-acting: Humalog®,
Intermediate-acting (NPH): Long-acting: Lantus®,
How is it best taken?
How is it best taken?
How is it best taken?
Short-acting (“regular”):
How is it best taken?
**Humalog® and Humulin®R and ** Humulin® N is not Apidra® are not available at FDL What are some possible side effects? Hypoglycemia (low blood sugar), weight gain
This is a summary of general information. Specific details about individual drugs may be important for you to know. Talk to your healthcare providers for more information.

Source: http://www.fdlrez.com/humanservices/medical/diabetes/Medications%20Nov%202012a.pdf