BRISTOL-MYERS SQ. Trailing: RELATIVE NYSE-BMY 22.35 RATIO 13.2 P/E RATIO 1.06 YLD 5.5% LINE Target Price Range TIMELINESS 1 Raised 12/5/08 2011 2012 2013 2 Raised 7/20/07 BETA .80 (1.00 = Market) 2011-13 PROJECTIONS Ann’l Total 20% 12% Insider Decisions F M A M J J A S O % TOT. RETURN 12/08 Institutional Decisions VL ARITH. Hld’s(000)143094514327331415621
Bristol-Myers Squibb was incorporated in 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 VALUE LINE PUB., INC. 11-13
Delaware in August 1933 as successor to a
10.75 11.40 Sales per sh 13.55 2.05 2.15 ‘‘Cash Flow’’ per sh 2.35 1.60 1.70 Earnings per sh A 1.85 1.28 Div’ds Decl’d per sh B■ 1.32
ration on October 4, 1989. The combination
.45 .45 Cap’l Spending per sh .55 6.65 7.25 Book Value per sh C 8.90
shares of Bristol-Myers for each share of 1988.8 1980.8 1953.5 1960.6 1937.4 1940.5 1942.4 1952.3 1962.4 1979.4 1974.0 1973.0 Common Shs Outst’g D 1970.0 13.5 Avg Ann’l P/E Ratio 19.0 .85 Relative P/E Ratio 1.25
pooling-of-interests accounting method. Avg Ann’l Div’d Yield 3.8% CAPITAL STRUCTURE as of 9/30/08 21260 22500 Sales ($mill) 26700 Total Debt $7902 mill. Due in 5 Yrs $1782 mill. 26.5% 27.0% Operating Margin 25.0% LT Debt $6120 mill. LT Interest $315.2 mill. 915 930 Depreciation ($mill) 980 3160 3355 Net Profit ($mill) 3645 Leases, Capitalized $49.0 mill. 23.0% 24.0% Income Tax Rate 24.0% 14.9% 14.9% Net Profit Margin 13.7% Pension Assets-12/07 $6.3 bill. Oblig. $6.8 bill. 6900 3500 Working Cap’l ($mill) 4000 6120 6100 Long-Term Debt ($mill) 6500 Pfd Stock None Common Stock 1,976,562,119 shs. 13150 14300 Shr. Equity ($mill) C 17530 as of 10/28/08 20.0% 19.5% Return on Total Cap’l 15.5% 24.0% 23.5% Return on Shr. Equity 20.5% MARKET CAP: $44.2 billion (Large Cap) 5.5% 6.5% Retained to Com Eq 6.0% CURRENT POSITION 76% 75% All Div’ds to Net Prof 71% ($MILL.) BUSINESS: Bristol-Myers Squibb Company manufactures proprie-
10/01/01. International operations represent 46% of sales (35% of
tary medical products, ethical pharmaceuticals, diagnostics, infant
operating profit); R&D, 16.9%. ’07 depreciation rate: 10.3%. Es-
formula, orthopedic implants, health and beauty aids. Major brand
timated plant age: 14 years. Has about 46,050 employees Officers
names include: Plavix ($4.8 billion in ’07 sales), Avapro, Pravachol,
& directors own 1% of stock (3/08 proxy). Chairman and CEO:
Coumadin, Reyataz, Sustiva, Baraclude, Erbitux, Taxol, Sprycel,
James M. Cornelius. Incorporated: DE. Addr.: 345 Park Ave., NY,
Ixempra, Abilify, Enfamil, Enfagrow. Acquired DuPont Pharma.
NY 10154. Tel.: 212-546-4000. Internet: www.bms.com. Bristol-Myers has a very healthy cash hoard. At the end of the third quarter,
gin, and a 13% hike in drug operation rev-
ANNUAL RATES Past Est’d ’05-’07 of change (per sh) to ’11-’13
$7.4 billion. And we look for that tally to
Nutritional unit sales. In 2009, we expect
rise by another $2 billion after Bristol sells
to an anticipated 10% in 2008. As the dol-
QUARTERLY SALES ($ mill.)
of BMY’s Nutritionals business in early
able to be less favorable. Also, a decrease
Mar.31 Jun. 30 Sep. 30 Dec. 31
2009 should net BMY another $1 billion. Abilify is likely. It remains to be seen how
new pipleine drugs, Sustiva, Sprycel, and
February, but we wouldn’t be surprised to
Reyataz, will perform in a recession, but
5622 21260
we suspect they will do fairly well against
5450 5500 5700 5850 22500
the generics and other brand-name drugs. EARNINGS PER SHARE A Although top-ranked, this issue has Mar.31 Jun. 30 Sep. 30 Dec. 31 subpar total return potential to 2011-
moves, however, we look for Bristol to up
2013. Near-term pipeline hopefuls, and
little chance of filling the earnings vacuum
.43 1.60 .40 .40 .45 .45 1.70
left by the patent expirations of BuSpar,
Pravachol, Taxol, and Glucophage, as well
QUARTERLY DIVIDENDS PAID B■
rights to more cancer treatments, are also
as decling growth of Plavix. Still, those in-
Mar.31 Jun.30 Sep.30 Dec.31
vestors interested in yield (and they are a
We look for share net of $1.60 in 2008 and $1.70 in 2009. Final-quarter share A) Based on avg. shares outstanding thru. ’97, 2Q ’04. (C) Includes intangibles. In ’07: $6328 million, Company’s Financial Strength
diluted thereafter. Next earnings report due late (B) Dividends historically paid in the first week $3.20/sh. Stock’s Price Stability
January. Excludes nonrecurring losses: ’98, of February, May, August, and November. ■ (D) In millions, adjusted for stock split. Price Growth Persistence
25¢. Includes extraordinary charge of $0.11 in Dividend reinvestment plan available. Earnings Predictability
2009, Value Line Publishing, Inc. All rights reserved. Factual material is obtained from sources believed to be reliable and is provided without warranties of any kind. THE PUBLISHER IS NOT RESPONSIBLE FOR ANY ERRORS OR OMISSIONS HEREIN. This publication is strictly for subscriber’s own, non-commercial, internal use. No part
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Therapeutisches Drug Monitoring im Rahmen der systemischen antimykotischen Therapie: Invasive Pilzinfektionen werden überwiegend durch Aspergillus spp . ( A. fumigatus ) und Candida spp . hervorgerufen und stellen lebensgefährliche Komplikationen dar. Aspergillosen imponieren nach Inokulation über den Respirationstrakt initial als Pneumonie und treten vor allem bei hämatologis
w w w. r e d l a n o . o r g ( E p u b a h e a d o f p r i n t ) Presentaciones orales Gliomas de bajo grado: analisis de 45 casos Robinson Rodríguez 1, Sonia Acuña1, Florencia Leyes1, Sebastián Ximénez1, Cristina Mara1, Ramiro Lima1, Diego Bertini1, Andrea Ríosi11 Unidad de Neuro-oncología, Departamento de Oncología, Hospital de Clínicas, Facultad de Medicina (Montevideo, Uru