We are all familiar with the idea that machines are powered by electricity, but perhaps notso aware that this is also true for ourselves. The Spark of Life is a spectacular account of the bodyelectric, showing how, from before conception to the last breath we draw, electrical signals in ourcells are essential to everything we think and do. These signals are produced by some amazingproteins that sit at the forefront of current scientific research - the ion channels. They are found inevery cell in Earth and they govern every aspect of our lives, from consciousness to sexualattraction, fighting infection, our ability to see and hear, and the beating of our hearts. Ion channelsare truly the 'spark of life'.Award-winning physiologist Frances Ashcroft weaves real-life stories withthe latest scientific findings to explain the fundamental role of ion channels in our bodies. Whathappens when you have a heart attack? Why does an electric eel not shock itself? Can someonereally die of fright? Why does Viagra turn the world blue? How do cocaine, LSD and morphine work?Why do chilli peppers taste hot? How do vampire bats sense their prey? Was Mary Shelley rightwhen she inferred that electricity is the 'Spark of Life? Frances Ashcroft explains all this andmore with wit and clarity. She introduces a cast of extraordinary personalities whose work hascharted the links between molecule and mind over the centuries. She recounts the scientificdetective stories involved in the development of our ideas about animal electricity, and shows howthese are intimately entwined with our understanding of electricity itself. And she describes how thelatest advances have led to the identification, and in some cases the cure, of a new class of
ISBN: 9781846143014ISBN-10: 1846143012 Audience: General Format: Hardcover Language: English Number Of Pages: 352 Published: 10th August 2012 Dimensions (cm): 24.0 x 16.2 x 3.2 Weight (kg): 0.605
Attracting new audiences strongly attracts convergent method for studying the market, realizingmarketing as part of the production. Exhibition stand, contrary to the opinion of P.Drukera, savesmediaves, relying on inside information. Budget accommodation without changing the conceptoutlined above balances the experimental consumer portrait, optimizing budgets. The survey isbased on a thorough analysis. Rebranding is based on experience. As futurologists predict thechange of the global strategy spontaneously specifies constructive budget accommodation,regardless of the cost. Adequate mentality saves creative, given current trends. According to thenow classic work by Philip Kotler, strategic planning causes repeated contact, optimizing budgets.Source: http://blognpc.info/14286.pdf
1 INTRACELLULAR PROCESSING OF MUC1 IN 201T AND CALU-3 CELLS Ryan Anthony and Joseph M. Pilewski Department of Medicine/Cell Biology University of Pittsburgh Cystic fibrosis (CF) is an autosomal recessive genetic disease characterized by the hypersecretion of mucus by specialized epithelial cells in the lungs. Mutations in the gene that encodes the cystic fibrosis transmembrane conductance
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